Smart Core Control, Steady as Ever: The Core Advantages of the Haoran Fermentation Tank
Ultimate cleanliness and full‑process aseptic assurance: Haoran products employ an integrated CNC polishing process to achieve deep surface treatment of the internal chamber, delivering a surface finish on all material‑contact areas of Ra ≤ 0.1–0.4 μm (EP grade)—an exceptionally high standard that eliminates microscopic crevices and dead corners where contaminants could accumulate. The tank lid integrates a quick‑release clamp and a triple‑stage aseptic sealing system, while critical interfaces such as manholes, sight glasses, and feed ports are designed to meet hygienic fluid‑handling standards. The system supports in‑situ steam sterilization (SIP) and online cleaning (CIP), enabling seamless closed‑loop operation from media preparation and high‑temperature hold sterilization through batch discharge.
Precision Environmental Parameter Control Expert:
Precise and efficient oxygen transfer: Equipped with a variable-speed, multi-stage impeller system featuring both straight‑blade and inclined‑blade designs, it supports two operating modes—cantilever shaft and bottom magnetic‑levitation shaft—and is paired with an annular jet diffuser to achieve precise dissolved‑oxygen (DO) gradient control, with DO saturation deviation maintained within ±0.5 ppm.
Highly stable temperature control: Combines a jacketed coil with an inverter‑controlled cooling‑medium regulation module, employing a multi‑point thermistor sensing network to maintain temperature fluctuations within ±0.3°C; includes a pre‑installed cryogenic liquid nitrogen nozzle interface to meet the demands of ultra‑low‑temperature fermentation.
Precise pH Control and Automatic Defoaming: An imported acid dosing pump and a peristaltic alkali pump dynamically adjust in real time based on biosensor data; a high-speed laser foam‑monitoring probe is integrated with a high‑pressure defoamer spray valve to continuously eliminate foam‑induced interference.
Intelligent Monitoring Module Integration: The equipment is equipped with an IoT edge‑processing terminal, fully compatible with OPC UA and Modbus TCP protocols, enabling dynamic acquisition and analysis of critical real-time parameters such as DO, temperature, pH, tank pressure, and feed rate. An optional high‑definition endoscopic panoramic camera system can be installed to monitor mycelial growth and floc conditions inside the fermenter, with AI‑based anomaly detection capabilities. All operational logs can be stored and exported in JSON format for GMP‑compliant production traceability and audit purposes.
Empowering Multiple Industries: Precisely Driving the Industrialization of Biotechnology
Upgrading the food and seasoning fermentation industry:

A major domestic condiment manufacturer uses Haoran’s custom-designed 10-ton fully automatic yeast propagation tanks, achieving a 12% increase in fermentation rate.
Soy sauce producers in the Southwest region have replaced traditional large‑tank fermentation with an array of 120‑square‑meter fiber‑optic bioreactors, reducing the production cycle by 30% and lowering fusel oil formation by 40%.
Breakthroughs in the biopharmaceutical field:

A certain recombinant protein drug CDMO employs a 100‑L Haoran bioreactor for high‑throughput expansion of the seed bank, increasing the cell density in the bioreactor from an OD600 of 120 to an OD600 of 240.
Vaccine manufacturers have deployed the Haoran tank cluster system in conjunction with a deep‑layer microcarrier formulation, successfully achieving high‑efficiency amplification of Vero cells.
A microbial formulation company has successfully implemented a modular, high-density microencapsulation fermentation system, effectively addressing the risk of bacteriophage infection in Bacillus strains.
Green Manufacturing of Bio-based Materials:

The bio‑PHA production project employs Haoran’s high‑pressure air‑agitated aerobic fermenters (operating pressure ≥ 1.2 MPa), effectively addressing the challenge of insufficient polymer chain extension.
An environmental technology company has deployed Haoran tanks to construct an anaerobic ammonium oxidation (anammox) system for treating landfill leachate, achieving an ammonia‑nitrogen removal rate of 98.5% and enabling the resource‑oriented reuse of industrial wastewater.
Upgrading Agricultural Biofermentation:

A large-scale biofertilizer manufacturer employs a five‑unit parallel Haoran deep‑liquid fermentation platform to propagate and amplify live microbial strains, boosting the viability of probiotics to 10^11 CFU/g.
The high-end organic agriculture park employs a micro-scale plant growth‑regulator fermentation system to achieve precision fermentation in the production of crop biostimulants.