Haoran Inactivated Tank: Building a Biosafety Defense Line, Empowering High-Risk Management Upgrades


Core Advantage: Triple Protection Ensures Absolute Security
1. Revolutionary Breakthrough in Inactivation Efficiency

Precise Synergy of High Temperature and High Pressure: Utilizing a double-layer FBE anti-corrosion jacket combined with a multi-segmented flow-guiding coil, the saturated steam penetration efficiency is enhanced by 40%. Meanwhile, the cavity maintains a uniform temperature distribution of 121°C with an accuracy of ±0.5°C, ensuring that even stubborn pathogens—such as thermophilic Bacillus subtilis spores—are eliminated at a rate of ≥6-log.
Chemical-physical dual-mode inactivation: Optionally equipped with a hydrogen peroxide (VHP) vaporization and spraying system or an acid-base chemical injection unit, enabling thorough degradation of special contaminants such as prions and heat-resistant endotoxins, with residual DNA/RNA fragments ≤10 pg/mL.
2. Biological Sealing and Protection System

Negative-pressure dual-lock sealing mechanism: The tank body utilizes laser welding with an integrated forming technique (weld seam porosity <0.01%), combined with a magnetically driven stirring and sealing system, effectively eliminating the risk of mechanical shaft seal leakage. Meanwhile, the chamber maintains a constant negative pressure of **-30 Pa**, complemented by a HEPA exhaust gas filtration system to ensure zero aerosol leakage.
Intelligent Protection System: Equipped with a pressure-sensitive membrane rupture monitoring module, this system automatically shuts off the feed pipeline and activates emergency cooling when abnormal pressure buildup occurs inside the inner container, effectively mitigating the risk of tank rupture.
3. Digital Full-Process Traceability

Equipped with an industrial IoT control terminal, it records in real time critical parameters such as temperature-pressure-time (T/P/t) curves and inactivator concentration, generating electronically signed reports compliant with 21 CFR Part 11.
Supports 3D dynamic thermal map analysis, automatically identifies cold spot areas, and provides recommendations for supplemental inactivation protocols. Audit-tracked data is stored for ≥10 years.
Deep applications across multiple industries: From laboratory to industrialization
Biopharmaceuticals: Safeguarding the Safety Chain for Vaccines and Blood Products
A national-level vaccine company has adopted Haoran's fully automated cell culture inactivation platform to inactivate rabies virus in Vero cell vectors, reducing the viral titer to ≤0.1 LD₅₀/mL and achieving WHO prequalification.
The blood products facility has introduced a low-temperature plasma inactivation system (operating at 37°C), which effectively preserves the activity of coagulation factors while achieving an HBV/HCV virus inactivation efficiency of ≥99.9999%.
Dangerous Chemicals: Achieving Harmless Transformation of High-Risk Waste
A leading agrochemical company has equipped itself with a group of organophosphorus wastewater inactivation tanks, utilizing an alkaline hydrolysis process (pH > 12, 80°C) to degrade the highly toxic methyl parathion into biodegradable small molecules, achieving a toxicity reduction rate of 99.8%.
The semiconductor factory uses a closed-loop inactivation system for cyanide-containing wastewater, which catalyzes the conversion of cyanide ions (CN⁻) into non-toxic N₂ and CO₂ using hypochlorite. The system boasts a treatment capacity of up to 5 tons per day.
Microbial Research: Strengthening the Laboratory's Biosecurity Wall
The BSL-3 laboratory is equipped with a double-door pass-through incubator for medium inactivation, which performs ultra-high sterilization of Mycobacterium tuberculosis-contaminated cultures at 135°C for 45 minutes. Exhaust gases undergo two-stage incineration treatment before being discharged, meeting the ISO Class 5 cleanroom standard.
The gene-editing company uses a CRISPR vector inactivation workstation, employing a combined UV-ozone treatment to completely degrade plasmid DNA and prevent the leakage of genetically engineered bacteria.
Food Industry: Breaking the Dilemma of Allergens and Toxins
Dairy companies utilize a β-lactoglobulin-specific inactivation tank, employing a unique enzymatic hydrolysis process to eliminate allergenic protein epitopes while preserving 80% of lactoferrin activity, thereby meeting the drinking needs of allergy-prone individuals.
The grain and oil processing plant has activated an aflatoxin degradation system, using ozone micro-nano bubble technology to convert B1 toxin into non-toxic B2a, with residual levels below 1 ppb.